Tuesday, 8 October 2013

Political drive to screen for Pre-Dementia


Dementia is a progressive and largely irreversible clinical syndrome that is characterised by a widespread impairment of mental function. This includes problems with memory loss, thinking speed, mental agility, language, understanding and judgement.  Dementia is a common condition that affects about 800,000 people in the UK. The risk of developing dementia increases as you get older, and the condition usually occurs in people over the age of 65.

Throughout the world there has been a ‘political drive’ to assess elderly patients for Dementia, due to the large amount diagnosed and past neglect of services and research in dementia has fuelled international calls for action and earlier treatment. The Alzheimer’s Society estimated that in 2005 there were 574,717 people in England with dementia. In addition the Society estimated that the total cost of dementia in the wider UK population totalled £17.03 billion, or an average of£25,472 per person with late-onset dementia. The NHS bears 8% £1.36 billion or £2.69 million per 100,000 population) of this total cost, as shown below.
The cost of £25,475 per person with late-onset dementia is the primary reason for the demand for screening or case finding of mild cognitive impairment and dementia, in aim to reduce NHS costs. In England, the government has announced that it will reward GP’s around £3600 annually, per practice for assessing patients aged over 75.This also includes those in a ‘at-risk group’ which is those patients with established diabetes or vascular disease. People with diabetes have an increased risk of developing dementia, due to high blood glucose concentrations which damage blood vessels, and the risk of vascular dementia increases with blood vessel damage. This is also being enforced in other places around the world such as in the United States, under the new Affordable Care Act which is a recent new health reform, the Medicare insurance programme will cover an annual wellness visit with a physician. This wellness visit will include detection of cognitive impairment or any measurable change in thinking abilities.

This screening process aiming to diagnose patients early will beneficial so healthcare assistants can give counselling and provides an opportunity for patients to organise financial affairs and future guardianship whilst they are still competent.

However the ‘political drive’ is controversial, because screening is not recommended by the UK National Screening Committee, Royal Australian College of General Practitioners guidelines or the US Preventative Services Task Force.  This is because there is no evidence for the usefulness or curative pharmacological intervention. A further reason is that only 5-10% of people with mild cognitive impairment progress to Dementia, therefore costs of screening may not outweigh the costs of early diagnosis. Furthermore many people who develop dementia do not meet the definitions of mild cognitive impairment before diagnosis. Also very interestingly, research has shown that the development of people with dementia is higher in people who don’t have symptoms of mild cognitive impairment than in those who do. A major issue created by screening, is adding increase risks to the patients: this is because there is no drugs to prevent the progression, many patients turn to therapies such as Vitamin E, cholinesterase inhibitors or memantine. These can increase damage to a patient’s health rather than improve it, for example cholinesterase inhibitors increase of hip fractures, syncope and pacemaker insertion.

It is difficult to assess whether the beneficial advantages of screening patients for cognitive impairment outweighs the negative risks and effects of the treatment. Nevertheless, within the UK and the US and many other places around the world they think it’s extremely worthwhile.

Reference:
http://www.mayoclinic.com/health/vascular-dementia/DS00934/DSECTION=risk-factors

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